Journal of Glycobiology
Open Access

Ingrid Cely

Publications

• Review Article
  Immune Response Modulation by Tumor-Secreted Glycosphingolipids
  Author(s): Ricardo D Lardone, Ingrid Cely, Peter A Sieling, and Delphine J Lee Ricardo D Lardone, Ingrid Cely, Peter A Sieling, and Delphine J Lee
  
  Although originally considered merely structural components of cellular membranes, glycosphingolipids (GSL) are now recognized as having critical effects on cellular physiology, including proliferation, differentiation, viral transformation and ontogenesis. In addition, a vast majority of human cancers have modified GSL composition compared to parental normal cells. These modifications may contribute to both tumor survival and exert striking effects on anti-tumor immunity. In this review, we discuss mechanisms of immune modulation by tumor-secreted GSL. .. View More»
  DOI: 10.4172/2168-958X.1000107

  Abstract PDF

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