Journal of Proteomics & Bioinformatics
Open Access

Ionel Iosif

Publications

• Research Article
  Computational Strategies for Drug Reprofiling
  Author(s): Serban San-Marina, Rajeesh Gupta and Ionel IosifSerban San-Marina, Rajeesh Gupta and Ionel Iosif
  
  This article introduces some of the recent developments in drug re-profiling with emphasis on how computational chemistry and biology approaches together with access to public databases can help generate new leads from existing drugs. It discusses the drawbacks of high-throughput (HTS) genomics and how the concepts of target polypharmacology can help speed up delivery of the next generation of drugs. Some of the successful strategies for drug re-profiling are presented and computational tools are discussed... View More»
  DOI: 10.4172/jpb.1000196

  Abstract PDF

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