Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Irena Lazarev
Israel
Review Article
Measles Virus: Association with Cancer
Author(s): Samuel Ariad, Irena Lazarev and Daniel Benharroch
Samuel Ariad, Irena Lazarev and Daniel Benharroch
Measles virus (MV) is a member of the paramyxovirus family of enveloped RNA viruses and one of the most infectious viral pathogens identified. Despite initial optimism that vaccination programs would eventually eradicate measles, reduced vaccination coverage against measles continues to result in outbreaks of measles. Mild or asymptomatic measles infections are common among measles-immune persons exposed to measles cases and may be the most common manifestation of measles during outbreaks in highly immune populations. Persistent, asymptomatic MV infections commonly persist in apparently healthy individuals. MV has been detected in several malignancies, including lung, breast, and endometrial cancers, as well as Hodgkin’s lymphoma. The presence of MV in these tumors was associated with distinct clinico-pathological characteristics: in lung cancer, older ages of patients and over .. View More»
DOI:
10.4172/2155-9899.S5-002