Journal of Clinical and Experimental Ophthalmology
Open Access

Jade Schiffman

Publications

• Research Article
  Significance of Anti-retinal Autoantibodies in Cancer-associated Retinopathy with Gynecological Cancers
  Author(s): Grazyna Adamus, Dongseak Choi, Anitha Raghunath and Jade SchiffmanGrazyna Adamus, Dongseak Choi, Anitha Raghunath and Jade Schiffman
  
  Background: The presence of autoantibodies (AAbs) is the primary serological indicator of autoimmunity. Cancerassociated retinopathy (CAR) is associated with AAbs and different types of cancer. The goal of the study was to examine the profile of serum autoantibodies in women with gynecological cancers with and without paraneoplastic visual manifestation. Methods: Retrospective studies of a cohort of 46 women with symptoms of CAR and gynecological tumors, including endometrial, cervical, ovarian, and fallopian tubes, 111 women with similar tumors without symptoms of CAR, and 60 age-matched healthy controls. Presence of serum AAbs and the identity of targeted antigens were performed by western blotting and their significance was evaluated using an Fisher’s exact test. Results: The patients with gynecological CAR ha.. View More»
  DOI: 10.4172/2155-9570.1000307

  Abstract PDF

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