Cell & Developmental Biology
Open Access

James D Richards

Publications

• Research Article
  Quantitative Analysis of Tendon Structural Integrity in Chickens using Fourier Transform-Second Harmonic Generation Imaging
  Author(s): Mayandi Sivaguru, James D Richards, Julia J Dibner, John Paul Eichorst, Terra D Wineman and Juxing Chen Mayandi Sivaguru, James D Richards, Julia J Dibner, John Paul Eichorst, Terra D Wineman and Juxing Chen
  
  Degenerative changes in tendons are common in human and land-dwelling vertebrates of all species, and are associated with both age and use. Tendon rupture and inflammation are common causes of lameness in broilers and breeders at multiple ages and has become a very important issue in the poultry industry attempts to analyze tendon health have relied primarily on visual assessment. The ability to conduct meaningful experiments on causes and interventions would be much improved by a direct assay of tendon structural integrity. The objective of this study is to test whether we can use Fourier transform-second harmonic generation (FT-SHG) imaging technique to quantify the differences in collagen fiber organization and nuclei morphology between normal and injured chicken tendons. Tendon injury/degeneration was induced by rearing chickens in wire-floor pens and feeding them an oxidized fat .. View More»
  DOI: 10.4172/2168-9296.1000140

  Abstract PDF

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