Journal of Chromatography & Separation Techniques
Open Access

Jan A Glinski

Publications

• Research Article
  Efficient, Baseline Separation of Pyrethrins by Centrifugal Partition Chromatography
  Author(s): Alan Wong and Jan A Glinski Alan Wong and Jan A Glinski
  
  Pyrethrins are natural pesticides present in the oil extracted from the flowers of Chrysanthemum cinerariaefolium. They are potent ion-channel neurotoxins which have higher selective toxicity for insects compared to mammals. These phytochemicals have an exceptionally safe environmental profile and are an attractive natural alternative to organophosphate insecticides currently used in agriculture. The oil extract contains six pyrethrins compounds, which are structurally related esters. Isolation of reference standards for pyrethrins and their derivatives in multi-gram quantities is a prerequisite for studying toxicity and soil degradation for these natural pyrethrins. Chromatography is difficult because of the high hydrophobicity and close structural similarity. The isolated pyrethrin compounds also have poor stability because they are photosensitive. To facilitate these studies, we ha.. View More»
  DOI: 10.4172/2157-7064.1000362

  Abstract PDF

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