Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access
ISSN: 2375-4508
+44 1478 350008
ISSN: 2375-4508
+44 1478 350008
Jane Frederick
United States
Research Article
Successful Outcomes of Fresh and Frozen Donor Ovum Cycles Among Recipients Using Oral Estradiol and Vaginal Progesterone Gel vs. Intramuscular and Vaginal Progesterone
Author(s): Robert Boostanfar and Jane FrederickRobert Boostanfar and Jane Frederick
Background: There is a paucity of data evaluating the efficacy of vaginal progesterone replacement in both fresh and frozen transfers of recipients of oocyte donors.
Method: This was a multicenter, IRB approved, retrospective analysis from January 2009 through June 2013 of 255 cycles among women less than 55 years of age who were oocyte recipients in an anonymous donor program. Oocyte recipients from fresh and frozen cycles received vaginal progesterone gel (Crinone 8%) 90 mg twice daily and oral estradiol 2 mg 2–3 times daily in a step-up protocol. The comparative groups of fresh and frozen donor oocyte cycles took progesterone intramuscular 50 mg once a day, 5 days prior to transfer, Progesterone 200 mg vaginal capsule beginning the day of transfer and Estrogen 2 mg orally three times daily continuing until the tenth week of pregnanc.. View More»
DOI:
10.4172/2375-4508.1000158