Journal of Clinical and Cellular Immunology

Journal of Clinical and Cellular Immunology
Open Access

ISSN: 2155-9899

+44 1223 790975

Janine Degen

Janine Degen

Germany

Publications
  • Review Article
    Emerging Roles of ADAP, SKAP55, and SKAP-HOM for Integrin and NF-κB Signaling in T cells
    Author(s): Amelie Witte, Janine Degen, Kathleen Baumgart, Natalie Waldt, Benno Kuropka, Christian Freund, Burkhart Schraven and Stefanie KlicheAmelie Witte, Janine Degen, Kathleen Baumgart, Natalie Waldt, Benno Kuropka, Christian Freund, Burkhart Schraven and Stefanie Kliche

    Adapter proteins are scaffolding proteins that lack enzymatic or transcriptional activity. They play a crucial role in the organization of signalosomes, which are molecular complexes involved in signal transduction. Here, we review some of the recent findings regarding the three cytosolic adapter proteins ADAP, SKAP55, and SKAP-HOM with respect to their role in T-cell adhesion, migration and proliferation... View More»
    DOI: 10.4172/2155-9899.S12-002

    Abstract PDF

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