Journal of Clinical & Experimental Dermatology Research
Open Access

Jason B Lee

Publications

• Research Article
  Is Warfarin Usage A Risk Factor for Cutaneous Calciphylaxis? A Retrospective Analysis
  Author(s): Kimberly A Tefft, Jonathan Andrews, Jason B Lee and Rakesh Gulat Kimberly A Tefft, Jonathan Andrews, Jason B Lee and Rakesh Gulat
  
  Currently the pathogenesis of cutaneous calciphylaxis, also known as calcemic uremic arteriolopathy, is poorly understood. We sought to evaluate potential risk factors for cutaneous calciphylaxis (CC), specifically warfarin usage prior to CC diagnosis, other anticoagulant usage prior to CC diagnosis, an elevated serum calcium level, an elevated serum phosphate level, a serum calcium and phosphate product greater than 50, hyperparathyroidism, and a history of chronic (stage III-V) kidney disease. We performed a retrospective analysis of all histopathologically confirmed cases of cutaneous calciphylaxis diagnosed at Thomas Jefferson University Hospital between January 1st 1990 and March 1st 2010. Of the thirteen study patients, five (38%) patients had a history of warfarin use, 12 (93%) of patients had elevated intact parathyroid hormone levels, and 12 (93%) of patients suffered from ch.. View More»
  DOI: 10.4172/2155-9554.1000114

  Abstract PDF

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