Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Research Article
Are Features of the Metabolic Syndrome Associated with Macular Thickness in Individuals without Diabetes Mellitus?
Author(s): KM Gooding, AC Shore, H von Lany, R Ling, M Mitra, CI Ball, D Mawson and JE TookeKM Gooding, AC Shore, H von Lany, R Ling, M Mitra, CI Ball, D Mawson and JE Tooke
Background: Maculopathy is a common feature at diagnosis of type 2 diabetes. However, it is not known whether macular thickening, a potential preclinical sign of macular oedema, occurs in individuals with risk factors for diabetes.
Purposes: To examine whether macular thickness is increased in individuals with features of the metabolic syndrome, namely waist circumference, blood pressure, and fasting levels of triglycerides, HDL-cholesterol and glucose in non-diabetic individuals.
Methods: 50 non-diabetic Caucasian individuals were recruited (25 males, age range: 26-78 years, BMI range: 20-46 kg/m2). Macular thickness, divided into fovea and the inner and outer temporal, nasal, superior and inferior quadrants, was assessed by Optical Coherence Tomography. Additional assessments included: arterial blood pressur.. View More»