Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Research Article
The Effect of Combined Intrathecal Morphine and Clonidine on Stress Response, Extubation Time and Postoperative Analgesia after Cardiac Surgery
Author(s): Mona Mohamed Mogahed, Jehan Mohammad Ezzat Hamed and Mohamed Shafik Elkahwagy
Mona Mohamed Mogahed, Jehan Mohammad Ezzat Hamed and Mohamed Shafik Elkahwagy
Background: Pain is a major complication after cardiac surgery, if it is poorly controlled, it will lead to more complication as respiratory depression, myocardial ischemia, delayed extubation, and more ICU stay, with the more analgesic consumption and patients suffering. Intrathecal morphine produces intense and prolonged analgesia and can be useful adjunct for controlling postoperative pain and facilitating early extubation after cardiac surgery. The addition of intrathecal clonidine to morphine allows the dose of intrathecal morphine to be reduced and reduces the risk of respiratory depression while maintaining good analgesia and allows early extubation. This randomized controlled study was carried out on 40 patients undergoing open cardiac surgery and was divided into two groups; group (I): is the control group (n=40) and group (II): is the morphine clonidine grou.. View More»
DOI:
10.4172/2155-6148.1000739