Clinical & Experimental Cardiology
Open Access

Jiali Li

Publications

• Research Article
  The Effect of High-Dose Simvastatin Therapy on Patients with Acute Cerebral Infarction
  Author(s): Xiaozhu Liu*, Huankun Liang, Kangyan Li, Jiali Li, Laiqing Li and Licheng Zhang Xiaozhu Liu*, Huankun Liang, Kangyan Li, Jiali Li, Laiqing Li and Licheng Zhang
  
  Cerebrovascular disease (CVD) accounts for the major cause of morbidity and mortality in industrialized countries. However, effects of high-dose simvastatin therapy on patients with acute cerebral infarction still unclear. In this study, the clinical efficacy of high-dose simvastatin on patients with cerebral infarction was investigated. A total of 180 patients with acute cerebral infarction were randomized divided into control group (n=60), high-dose simvastatin (HDS) group (n=60) and low-dose simvastatin (LDS) group (n=60). Control group, HDS group and LDS group received conventional treatment, conventional treatment together with simvastatin 80 mg/d and conventional treatment as well as simvastatin 40 mg/d respectively for 3 months. Biochemical indices, neurological deficit and plaque thickness and volume were assessed and recorded after treatment. After simvastatin treatment, the .. View More»
  DOI: 10.4172/2155-9880.1000527

  Abstract PDF

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