ISSN: 2155-9554
+44 1478 350008
Jonathan Sutton
Derriford Hospital, Derriford Rd, Plymouth PL6 8DH,
Case Report
A Case of Acrodermatitis Enteropathica
Author(s): Jonathan Sutton and Thurein Newin
Jonathan Sutton and Thurein Newin
Clinicians should be mindful of all paediatric skin diseases, which present in a similar manner during the first months of life. Acrodermatitis enteropathica (AE) is a rare, bullous disorder that has a significant impact on the child’s quality of life and is fatal if untreated. AE is either a recessively inherited or a transiently acquired disorder. The hereditary form is caused by a genetic mutation in intestinal zinc absorption whereas the acquired form is caused by low nutritional intake or decreased peripheral release of zinc from the blood. This case report describes AE which manifested in a similar way to other blistering skin disorders, but showed a dramatic clinical improvement to oral zinc therapy. AE is characterised by a triad of periorificial and acral dermatitis, diarrhoea and alopecia. Both forms of AE affect males and females equally. The cutaneous lesions are ann.. View More»
DOI:
10.4172/2155-9554.1000329