Clinical & Experimental Cardiology
Open Access

Juan R Gimeno

Publications

• Research Article
  Lack of Peri-Procedural Myocardial Necrosis Reduction from Abciximab in Patients on Dual Antiplatelet Therapy Revascularized with Rotational Atherectomy
  Author(s): Juan Garca-Lara, Eduardo Pinar-Bermdez, Javier Lacunza-Ruiz, Ral Valdesuso-Aguilar, Jos A Hurtado, Juan R Gimeno and Mariano Valds-Chvarri Juan Garca-Lara, Eduardo Pinar-Bermdez, Javier Lacunza-Ruiz, Ral Valdesuso-Aguilar, Jos A Hurtado, Juan R Gimeno and Mariano Valds-Chvarri
  
  Rotational atherectomy allows plaque remodeling in severely calcified lesions and, prior to the adoption of clopidogrel as standard therapy, small trials showed that abciximab reduces transient hypoperfusion associated with the procedure. However, no studies have evaluated it among patients receiving dual antiplatelet therapy. This study aimed to evaluate whether abciximab reduces procedure-related myocardial injury in a non-selected population of patients receiving dual antiplatelet therapy. The study comprised a retrospective review of a nonselected cohort of 139 consecutive procedures of rotational atherectomy performed in patients pre-treated with dual antiplatelet therapy. Abciximab was administered in 48 (34.5%) patients, whereas 91 (65.5%) did not receive it. The only difference between groups was a higher rate of diabetes mellitus in the abciximab group (89% vs. 51%, p=0.001)... View More»
  DOI: 10.4172/2155-9880.1000270

  Abstract PDF

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