Gynecology & Obstetrics

Gynecology & Obstetrics
Open Access

ISSN: 2161-0932

Julio Casoy

Julio Casoy

Brazil

Publications
  • Research Article
    Treatment of Refractory Endometriosis-Related Pain with Vaginal Gestrinone in Pentravan Associated with Pinus Pinaster Extract and Resveratrol: A Preliminary Study
    Author(s): Hugo Maia Jr, Clarice Haddad, Moura Hirsch MCD, Wilson Saback and Julio Casoy Hugo Maia Jr, Clarice Haddad, Moura Hirsch MCD, Wilson Saback and Julio Casoy

    Introduction: Sexual dysfunction is common in patients with endometriosis and in the majority of cases the cause of sexual dysfunction is pain. The aim of this study was to investigate the effect of a combination of vaginal gestrinone with oral pinus pinaster extract and resveratrol on the pain scores of patients with deep endometriosis refractory to previous hormone treatment. Methods: Fifteen patients were treated with a combination of 5 mg of vaginal gestrinone in Pentravan® (Fagron, the Netherlands) three times a week and 100 mg of oral pinus pinaster extract (Fagron, the Netherlands) together with 30 mg of resveratrol (Fagron, the Netherlands) daily. Results: Mean pain score was 9 prior to treatment, reducing significantly to 3 (p=0.03) and 0.5 (p=0.004) after 1 and 2 months of treatment, respectively. Aft.. View More»
    DOI: 10.4172/2161-0932.1000246

    Abstract PDF

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