Virology & Mycology
Open Access
ISSN: 2161-0517
ISSN: 2161-0517
Julius N
Cameroon
Research Article
HBV and HCV Seroprevalence and the Predominant HCV Genotypes in a Hospital Setting in Cameroon
Author(s): Marceline DN*,Gaëlle FKA,Julius N,Paul MFMarceline DN*,Gaëlle FKA,Julius N,Paul MF
Infectious diseases are a substantial threat to global health. Hepatitis viral infections are life threatening infections, responsible for most liver cirrhosis and cancers. In order to determine the seroprevalence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections; as well as the HCV genotypes of the collected isolates, a study was conducted at a hospital setting in Cameroon. Enzyme immunoassays were used for HBV and HCV screening tests; HCV genotypes and subtypes were determined using standard molecular biology and genomic techniques that involved RT-PCR, gene cloning, DNA sequencing, and bioinformatics tools. The results showed that 14.15% of the study populations were screened HBV positive; whereas 24.82% were diagnosed HCV positive. The seroprevalence was higher in men: 12.75% and 16.1% respectively for HBV and HCV infections. The majority of HBV infected were young.. View More»
DOI:
10.4172/2161-0517.1000178