Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Junfang Xian
China
Research Article
Non-invasive Evaluation of Cerebrospinal Fluid Pressure in Ocular Hypertension: The Beijing Intracranial and Intraocular Pressure Study
Author(s): Xiaobin Xie, Weiwei Chen, Zhen Li, Ravi Thomas, Yong Li, Junfang Xian, Diya Yang, Huaizhou Wang, Jun Feng, Shoukang Zhang, Lixia Zhang, Ruojin Ren, Ningli Wang
Xiaobin Xie, Weiwei Chen, Zhen Li, Ravi Thomas, Yong Li, Junfang Xian, Diya Yang, Huaizhou Wang, Jun Feng, Shoukang Zhang, Lixia Zhang, Ruojin Ren, Ningli Wang
Objective: To compare the orbital CSFP and trans-lamina cribrosa pressure difference (TLCPD) determined noninvasively in Ocular Hypertension (OH) and controls, and study its association with the estimated risk of conversion to glaucoma.
Design: Cross-sectional observational study.
Participants: 19 subjects with OH recruited from the Tongren Eye Center and 23 controls enrolled in the Beijing Intracranial and Intraocular Pressure Study between June 2010 to December 2013.
Methods: Magnetic resonance imaging was used to measure orbital subarachnoid space width (OSASW) at 3, 9 and 15 mm posterior to the globe. The CSFP (mmHg) was estimated from a published formula as 17.54 × MRI derived OSASW at 15 mm behind the globe +0.47 × body mass index +0.13 × mean arterial blood pressu.. View More»
DOI:
10.4172/2155-9570.1000672