Biochemistry & Pharmacology: Open Access
Open Access

Karunakar Shukla

Publications

• Review Article
  Biosurfactants: A New Pharmaceutical Additive for Solubility Enhancement and Pharmaceutical Development
  Author(s): Sandeep Singh Bhadoriya, Narendra Madoriya, Karunakar Shukla and Parihar MS Sandeep Singh Bhadoriya, Narendra Madoriya, Karunakar Shukla and Parihar MS
  
  Biosurfactants are structurally diverse group of surface-active substances produced by microorganisms. At present, biosurfactants have gained importance in the pharmaceutical, biomedical, cosmetic and food industry, with a high added value, are still developing. Surfactants have numerous uses in pharmaceuticals, for solubilization of hydrophobic drugs in aqueous media, as components of emulsion or surfactant self-assembly vehicles for oral and transdermal drug delivery, as plasticizers in semisolid delivery systems, and agents to improve drug absorption and as penetration enhancer. Many pharmaceuticalgrade surfactants consist of saccharide- or polyol-fatty acid esters or fatty alcohol ethers that are biosurfactant. This article describes classical and new biosurfactants’ producing bacteria along with their significant role as pharmaceutical additives in development of pharmaceut.. View More»
  DOI: 10.4172/2167-0501.1000113

  Abstract PDF

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