ISSN: 2167-7700
Kaushik Roy
India
Review Article
Current Understanding of Epidemiology, Genetic Etiology and Treatment of
Gliomas from Indian Population
Author(s): Rajib Mukherjee, Tapas K Das, Kaushik Roy and Joydeep Mukherjee
Rajib Mukherjee, Tapas K Das, Kaushik Roy and Joydeep Mukherjee
Tumors of the central nervous system (CNS) consist of 1-2% of the total cancer spectrum. Gliomas are the most common tumors within the CNS. These tumors originate from glial cells or glial precursor cells. Tumors originates from astroglial cells are known as astrocytoma, oligodendroglioma originates from oligodendroglial cells, oligoastrocytoma are mixed tumor containing cellular property of both astrocytes and oligodendrocytes and ependymal cells gives rise to ependymoma. The World Health Organization (WHO) classification of central nervous system tumors separates glioma into four grades, in which grade I and II are defined as low grade whereas grade III and IV are classified as high grade (also known as malignant glioma). Malignant glioma includes anaplastic glioma (anaplastic oligodendroglioma, anaplastic astrocytoma, and anaplastic oligoastrocytoma) and glioblastoma. With current .. View More»
DOI:
10.4172/2167-7700.1000203