ISSN: 2155-6148
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Kenneth Martay
Tanzania
Research Article
Effects of Vasoactive Agents on Blood Loss and Transfusion Requirements During Pre-Reperfusion Stages of the Orthotopic Liver Transplantation
Author(s): Alexander A. Vitin, Kenneth Martay, Youri Vater, Gregory Dembo and Marlena MaziarzAlexander A. Vitin, Kenneth Martay, Youri Vater, Gregory Dembo and Marlena Maziarz
Objective: To evaluate the effects of vasoactive drugs, specifi cally low-dose vasopressin and phenylephrine infusions, on blood loss / transfusion requirements during dissection and anhepatic (pre-reperfusion) stages of orthotopic liver transplantations.
Methods: A retrospective analysis of 110 orthotopic liver transplantation (OLT) cases was performed. The variables studied were: blood loss before and after reperfusion of the liver graft; blood volumes returned by cell-saver and amounts of transfused blood products; amounts of infused colloids and crystalloids; hemodynamic parameters such as MABP, MPAP, CO/CI, SVR; dosage of vasoactive drugs. Short – and long-term outcome measures included length-of stay (LOS), ICU LOS, 48 –hours return to the OR rate, incidence of the primary non-function of the liver graft, amounts of fresh f.. View More»
DOI:
10.4172/2155-6148.1000104