Journal of Clinical and Experimental Ophthalmology
Open Access

Kenneth O Simbiri

Publications

• Case Report
  Bilateral Lacrimal Gland Mantle Cell Lymphoma: A Case Report and Review of the Literature
  Author(s): Cristiana Bellan, Polito Maria Sole, Barbarino Marcella, Polito Ennio, Kenneth O Simbiri, and Antonio Giordano Cristiana Bellan, Polito Maria Sole, Barbarino Marcella, Polito Ennio, Kenneth O Simbiri, and Antonio Giordano
  
  Background: In this report we will describe a case of mantle cell lymphoma (MCL) in the conjunctiva and underlying clinical, histologic, immunological and genetic findings jointly with review of current literature. Case presentation: Here we report a case of MCL presenting as bilateral conjunctival masses of a period of over four in a 70-year-old man. Method and results: Histological examination revealed a proliferation of monotonous small-to-medium-sized lymphoid cells with cleaved nuclei in the subconjunctiva. The lymphoid infiltrate expressed CD20, CD5, BCL-2, cyclin D1, and the transcription factor SOX11. Conclusion: We suggest a more focused approach to differential diagnosis of this cancer, as MCL is a more aggressive disease than other entities. Due to the rarity of this lymphoma a multidis.. View More»
  DOI: 10.4172/2155-9570.1000615

  Abstract PDF

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