Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Khaled Ahmed Yassen
National Liver Institute-Menoufiya University,
Egypt
Research Article
Inhaled Desflurane vs. Propofol for Postoperative Sedation Guided with Patient State Index of SEDline in Mechanically Ventilated Liver Transplant Recipient
Author(s): Khaled Ahmed Yassen, Eman Kamal EL-Deen Awaad, Emad Kamel Refaat, Neveen Mostafa Soliman and Magda Fouad YehiaKhaled Ahmed Yassen, Eman Kamal EL-Deen Awaad, Emad Kamel Refaat, Neveen Mostafa Soliman and Magda Fouad Yehia
Background: Monitoring sedation depth with appropriate sedative choice can reduce over sedation and associated side effects. Objectives: To compare Desflurane (Des) vs. Propofol (P) sedation with regards to, haemodynamics, recovery profiles, side effects and costs. Design: A prospective randomized hospital based comparative study. Setting: In a single centre between May 2012 and December 2014. Patients: Sixty mechanically ventilated liver recipients were assigned randomly to receive postoperative sedation either with inhalational Des in air/oxygen 1 litre min-1 or intravenous P 4 mg/kg/hr. Interventions: Recovery time and response to eye opening was recorded. Memorization of five words, Trieger dot test, and digit symbol substitution tests were applied. The Patient State Index (PSI) by SEDLine Sedation Monitor (Masimo, Irvin, CA) was used to target adequate depth of sedation (50-75) i.. View More»
DOI:
10.4172/2155-6148.1000623