ISSN: 2167-0420
Khan A
Khyber Teaching Hospital,
Peshawar-25000
Pakistan
Research Article
Serum CA 125 is a Biomarker of Tuberculous Peritonitis and its Inflammatory
Severity in Female Patients
Author(s): Khan A*, Haider I, Ayub M and Tahir AA
Khan A*, Haider I, Ayub M and Tahir AA
Background: The tumor marker CA 125 is commonly used in the screening and diagnosis of ovarian malignancy. However, recent studies have proven a limited role for CA 125 as a diagnostic marker for ovarian cancer. Moreover, it is often elevated in non-cancerous and inflammatory conditions as well. Aims: To evaluate the utility of CA 125 in the workup of intestinal tuberculosis/ tuberculous peritonitis in female patients.
Methods: In this observational study, patients with ascites were divided into two groups; tuberculous (group A), and non-tuberculous (group B). Each group had serum CA 125 measured and compared using independent sample t-test. CA 125 was correlated with ESR by using Pearson’s correlation test.
Results: CA 125 was higher in patients with tuberculous peritonitis. (N=20, M=117.75, SD=35.. View More»
DOI:
10.4172/2167-0420.1000345