ISSN: 2161-038X
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Kirsten S. Eckstrum
Tanzania
Special Issue Article
Localization of C-Fos-Induced Growth Factor (Figf) mRNA Expression in the Mouse Uterus during Implantation
Author(s): Charles A Scott, Kirsten S. Eckstrum and Brent M. Bany
Charles A Scott, Kirsten S. Eckstrum and Brent M. Bany
The purpose of this study was to characterize the localization of Figf mRNA in the mouse uterus during embryo implantation. Strong Figf mRNA hybridization signals wereseen in the primary decidual zone just after the onset of implantation from Days 4.5-6.5. On Day 7.5, this expression continued around the conceptus, but in addition we observed high expression of Figf mRNA in the endothelial cells that line the forming vascular sinusoids in the lateral mesometrial decidua. Interestingly, on Days 8.5 this high expression continued in the endothelial cells of sinusoids in the lateral mesometrialdecidual tissue but not in the decidual cells surrounding the conceptus. As implantation and placental development finished, Figf mRNA expression remained in the endothelial cells of the sinusoids and spiral arterioles of the decidua basalis. Interestingly, Flt4 mRNA was localized to the endothelia.. View More»
DOI:
10.4172/2161-038X.S1-003