Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
KM Gooding
Diabetes and Vascular Medicine, Institute of Biomedical and Clinical Science, Peninsula Medical School,
Barrack Road, Exeter, EX2 5AX
Research Article
Are Features of the Metabolic Syndrome Associated with Macular Thickness in Individuals without Diabetes Mellitus?
Author(s): KM Gooding, AC Shore, H von Lany, R Ling, M Mitra, CI Ball, D Mawson and JE TookeKM Gooding, AC Shore, H von Lany, R Ling, M Mitra, CI Ball, D Mawson and JE Tooke
Background: Maculopathy is a common feature at diagnosis of type 2 diabetes. However, it is not known whether macular thickening, a potential preclinical sign of macular oedema, occurs in individuals with risk factors for diabetes.
Purposes: To examine whether macular thickness is increased in individuals with features of the metabolic syndrome, namely waist circumference, blood pressure, and fasting levels of triglycerides, HDL-cholesterol and glucose in non-diabetic individuals.
Methods: 50 non-diabetic Caucasian individuals were recruited (25 males, age range: 26-78 years, BMI range: 20-46 kg/m2). Macular thickness, divided into fovea and the inner and outer temporal, nasal, superior and inferior quadrants, was assessed by Optical Coherence Tomography. Additional assessments included: arterial blood pressur.. View More»