Clinical & Experimental Cardiology
Open Access
ISSN: 2155-9880
+44 1300 500008
ISSN: 2155-9880
+44 1300 500008
Kofoworola Olajire Awotedu
Mthatha, Eastern Cape
South Africa
Research Article
Indices of Cardiovascular Function Derived from Peripheral Pulse Wave Analysis Using Radial Applanation Tonometry in HIV Positive Patients from Mthatha District of South Africa
Author(s): Kofoworola Olajire Awotedu, Rajiv Erasmus, Abolade Ajani Awotedu and Ambrose Vincent NamugowaKofoworola Olajire Awotedu, Rajiv Erasmus, Abolade Ajani Awotedu and Ambrose Vincent Namugowa
Background: HIV patients are suspected to have increased arterial stiffness which may contribute to a higher risk of coronary atherosclerosis. Invasive techniques are of limited value, hence in this study, the use on a noninvasive method was applied. The objective of the study was to see if there is increased arterial stiffness in HIV patients using applanation tonometry of the radial artery, consequently leading to cardiac dysfunction resulting in myocardial ischemia.
Methods: 169 participants took part in the study between December 2012 and June 2013. There were 63 HIV positive participants, 52 HIV negative participants, and 54 HIV treatment naive participants. Augmentation index (AIx (75), Ejection duration index (ED%) and sub-endocardial variability ratio (SEVR) and other parameters of interest were measured using arterial wave reflectio.. View More»
DOI:
10.4172/2155-9880.1000374