Journal of Hematology & Thromboembolic Diseases
Open Access
ISSN: 2329-8790
+44 1478 350008
ISSN: 2329-8790
+44 1478 350008
Kostal M
4th Department of Internal Medicine-Hematology, University Hospital and Medical School, Charles University,
Hradec Kralove
Czech Republic
Research Article
Risk and Prognostic Factors in Cerebral Venous Thrombosis
Author(s): Kostal M, Krajickova D, Ivanova E, Gabalec F, Vrbacky F, Sadilek P and Dulicek PKostal M, Krajickova D, Ivanova E, Gabalec F, Vrbacky F, Sadilek P and Dulicek P
Objective and design: Cerebral venous thrombosis (CVT) differs from deep venous thrombosis (DVT) in prognosis, risk factors and treatment. We analyzed data gathered in our prospective CVT single-center registry in search of risk and prognostic factors. Data from 73 patients were available.
Results: JAK2 mutation (11%) and Leiden mutation of factor V (11%) were the most common among genetic risk factors. The most common acquired risk factor was the use of combined hormonal contraception (COC) or hormonal replacement therapy (HRT) in 64% of female patients. No specific cause was found in 22% of cases. Complete recanalization was present in 44% of cases, more often in female than in male (p=0.0287) and in younger patients (p=0.045). We found final mRS score one and higher in 29% of patients. These patients did not use COC/HRT (p=0.021) or did not .. View More»
DOI:
10.4172/2329-8790.1000278