Journal of Clinical Toxicology
Open Access

Krishnamurthy NB

Publications

• Research Article
  Assessment of Lead Toxicity Using Drosophila melanogaster as a Model
  Author(s): Blessy Baby Mathew and Krishnamurthy NB Blessy Baby Mathew and Krishnamurthy NB
  
  Objectives: Lead is recognized as a serious pollutant on the basis of its persistence, toxicity, bioaccumulation and extensive use in industry. Exposure to lead results in a number of cytogenetical effects on freshwater biota which adversely affects the population, including reducing the rate of cell division and inducing mutations. In order to assess the toxicity of lead, a reliable model of Drosophila melanogaster was taken and experiments were carried out by maintaining a control set and experimental sets with varied concentrations of lead. Methods: The toxicity of lead was studied by varying the lead concentrations from 20-60 ppm in the food media that was given to the fruit flies. Studies on the larval, pupal and adult stages of the flies were done, including the reproductive and locomotion efficiency of the flies. .. View More»
  DOI: 10.4172/2161-0495.1000380

  Abstract PDF

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