Clinical & Experimental Cardiology
Open Access

Krystof Slaby

Publications

• Research Article
  Hemodynamics and Exercise Tolerance after Senning Operation for Transposition of Great Arteries and Its Limiting Factors: A Longitudinal Study
  Author(s): Viktor Tomek*, Jiri Radvansk, Theodor Adla, Vaclav Chaloupecky, Krystof Slaby, Jan Pokorny, Michal Prochazka, Petra Antonova and Jan Janousek Viktor Tomek*, Jiri Radvansk, Theodor Adla, Vaclav Chaloupecky, Krystof Slaby, Jan Pokorny, Michal Prochazka, Petra Antonova and Jan Janousek
  
  Objectives: The purpose of this longitudinal study was to assess hemodynamics and exercise capacity in patients after Senning operation and to determine its limiting factors. Methods: 87 long-term survivors of the Senning operation for transposition of great arteries were recruited for a longitudinal follow-up study consisting of two cross-sectional evaluations at a mean of 12.6 and 22.6 years after surgery, respectively. The protocol included a questionnaire, echocardiography, radionuclide angiocardiography, magnetic resonance imaging and cardiopulmonary exercise test. Decreased exercise capacity was defined as maximum oxygen uptake <-2 Z-scores. Results: Hemodynamic variables (right ventricular function and degree of tricuspid regurgitation) and chronotropic competence did not change significantly with time. D.. View More»
  DOI: 10.4172/2155-9880.1000437

  Abstract PDF

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