Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
ISSN: 2155-6148
Kyoko Asayama
Hiroshima University Hospital, Anesthesiology and Critical Care, 1-2-3 kasumi, Minami-ku, Hiroshima, 734-8551,
Japan
Research Article
Intraoperative Use of Large Volume of Hydroxyethyl Starch 70/0.5 Affects Postoperative Serum Creatinine Level-A Retrospective Study
Author(s): Kyoko Asayama, Michiyoshi Sanuki, Noboru Saeki, Hiroshi Hamada and Masashi KawamotoKyoko Asayama, Michiyoshi Sanuki, Noboru Saeki, Hiroshi Hamada and Masashi Kawamoto
Background: A 6% hydroxyethyl starch (Hespander®, Fresenius-Kabi Japan; HES) solution is generally used for perioperative fluid optimization, though intraoperative use of large amounts is regulated because of possible renal failure or other complications. On the other hand, some studies found that HES70/0.5, with the lowest molecular weight and molar substitution rate, did not affect renal function. In this retrospective study, we investigated the effect of intraoperative use of a large volume of HES70/0.5 on postoperative renal function.
Methods: Hospital electronic medical records of adult patients who had undergone surgery with general anesthesia without blood transfusion were retrospectively reviewed. Those with an intraoperative administration of ≥ 2000 ml of HES were classified as the HES group, while patients who received <100.. View More»
DOI:
10.4172/2155-6148.1000455