Anesthesia & Clinical Research
Open Access
ISSN: 2155-6148
+44 1223 790975
ISSN: 2155-6148
+44 1223 790975
Lai Wei
Tanzania
Research Article
Randomized Double Blind Control Study Comparing the Efficacy of
Intracuff Alkalinized Lidocaine to Low Dose Remifentanil Infusion in
Attenuating the Endotracheal Tube Induced Emergence Phenomena
Author(s): Rashmi Vandse, Karina Castellon-Larios, Jeffrey Fujii, Somayah Melibary, Lai Wei, Sherry Nashed and Sergio BergeseRashmi Vandse, Karina Castellon-Larios, Jeffrey Fujii, Somayah Melibary, Lai Wei, Sherry Nashed and Sergio Bergese
Emergence from general anesthesia is often complicated by the endotracheal tube (ETT) induced airway and circulatory reflexes which can lead to potentially dangerous complications. Considerable research has been focused on prevention of these emergence phenomena (EP). Nevertheless, the problem is still far from its final solution.
Objective: To compare the efficacy of intracuff alkalinized lidocaine (ICL) vs low dose remifentanil infusion in attenuating the ETT-induced EP. Methods: 120 ASA I-III patients, aged 18-65 years, were randomly assigned to receive intracuff alkalinized lidocaine (2% lidocaine mixed 1:1 with 1.4% NaHCO3) or an intravenous (IV) remifentanil infusion (0.05-0.5 mcg/ kg/min) combined with intracuff saline during desflurane-based general anesthesia. At the end of surgery, after desflurane was turned off in the assigned group, low dose rem.. View More»
DOI:
10.4172/2155-6148.1000435