ISSN: 2329-8901
Laïla Haddioui
France
Research Article
Probiotic Properties of Lactobacilli that could be Used Against Periodontitis
Author(s): Johan Samot, Haouaria Belkhelfa, Laïla Haddioui and Cécile Badet
Johan Samot, Haouaria Belkhelfa, Laïla Haddioui and Cécile Badet
Bacterial competitiveness appears to be an efficient way to fight pathogenic oral flora. This competition may be facilitated by probiotics, particularly in periodontal diseases. The aim of this study was to investigate the probiotic properties of 61 clinical isolates of oral lactobacilli. The inhibitory activity of the tested strains against periodontopathogens was assessed with the agar overlay technique. The results obtained, as well as those resulting from previous work, led us to select the nine most promising strains on which we conducted further tests, such as evaluating their coaggregation capacities with various oral species and the production of proinflammatory cytokines by PBMC. We also evaluated the safety of the probiotics by assessing their sensitivity to antibiotics. Their possible involvement in halitosis was investigated by testing their ability to produce volatile sul.. View More»
DOI:
10.4172/2329-8901.1000180