ISSN: 2155-9554
+44 1478 350008
Lane Neidig
Tanzania
Review Article
Psoriasis and Fat-soluble Vitamins: A Review
Author(s): Elizabeth Usedom, Lane Neidig, Herbert B. Allen
Elizabeth Usedom, Lane Neidig, Herbert B. Allen
Fat-soluble vitamins exhibit numerous routes of immune modulation and specifically alter a variety of pathways in psoriasis pathology. Psoriasis, a chronic immune-mediated disease, often requires a combination of topical, oral, and occasionally, subcutaneous or intravenous therapies making disease management complex. With the complexity of treatment, patient adherence is reduced. Vitamin supplementation as an adjunctive treatment would minimize potential adverse effects from systemic medication, increase patient adherence and decrease overall cost. While vitamin A and D are effective topically, oral supplementation is not currently a mainstay of therapy although data exists to support such supplementation. Data on vitamin E and K implicate the significant role each has in the alteration of the inflammatory cascade responsible for psoriasis. Research showing fat-soluble vitamin deficie.. View More»
DOI:
10.4172/2155-9554.1000421