Chemotherapy: Open Access

Chemotherapy: Open Access
Open Access

ISSN: 2167-7700

+44 1223 790975

Lanxin Lin

Lanxin Lin

Indiana

Publications
  • Review
    Landscape of Circular RNAs in the Clinical Application of Digestive System Neoplasm
    Author(s): Jian Zhou, Kai Fu, Yun Hu, Ran Qin, Lanxin Lin, Hongyong Cao and Wei-Wei Tang Jian Zhou, Kai Fu, Yun Hu, Ran Qin, Lanxin Lin, Hongyong Cao and Wei-Wei Tang

    It has been confirmed that noncoding RNAs (ncRNAs) play an important role in cellular development, differentiation, proliferation and apoptosis of various carcinomas. As a member of the ncRNAs family, circular RNAs (circRNAs) are getting new research hotspots because of their newly discovered and numerous potential functions such as acting as microRNA (miRNA) sponges and binding to RNA-binding proteins (RBPs) to modulate the gene transcription. Herein, we review the current understanding of the roles of circRNAs in the clinical application of digestive system neoplasm and provide a new insight into the potential implications in the diagnosis and targeted therapy of digestive system carcinomas. .. View More»
    DOI: 10.4172/2167-7700.1000251

    Abstract PDF

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