ISSN: 2155-6148
+44 1223 790975
Lars Berggren
Sweden
Research Article
Does Depth of Anesthesia Influence Postoperative Cognitive Dysfunction or Inflammatory Response Following Major ENT Surgery?
Author(s): Pether K Jildenstål, Jan L Hallén, Narinder Rawal and Lars BerggrenPether K Jildenstål, Jan L Hallén, Narinder Rawal and Lars Berggren
The aim of this study was to evaluate the role of depth of anesthesia on POCD after major ENT surgery and to assess changes in postoperative inflammatory markers in patients undergoing major ENT surgery. Thirty two patients aged 40 to 94 yrs, scheduled for surgery under general anesthesia were randomly assigned to one of two groups. In group A (AEP group) depth of anesthesia (DOA) was measured with auditory evoked potential (AEP). In the control group (group C) DOA was monitored according to clinical signs. Cognitive function was evaluated using Mini-Mental State Examination (MMSE), Confusion Assessment Method (CAM) and Cognitive Failure Questionnaire (CFQ). Inflammatory markers were measured before and after anesthesia. Perioperative requirements for desflurane and fentanyl were s.. View More»
DOI:
10.4172/2155-6148.1000220