Medicinal & Aromatic Plants
Open Access

Lépengué AN

Publications

• Research Article
  Antihypertensive Potential of Aqueous Extract of Nephrolepis biserrata Leaves on Toad Aorta
  Author(s): Ibrahim B, Attéké Nkoulémbéné C, Mounguengui S, Lépengué AN, Issembé Azizet Y, Akoué NSI G, Souza A and M’batchi B Ibrahim B, Attéké Nkoulémbéné C, Mounguengui S, Lépengué AN, Issembé Azizet Y, Akoué NSI G, Souza A and M’batchi B
  
  Of our ethnobotanic investigations in the district of Franceville, on 30 requested people, 20 answered the survey questionnaire. The present study aims at evaluating the hypotensive activity of Nephrolepis biserrata (NB) used by Ndoumou in the province of Haut-Ogooué in Gabon to treat or prevent against arterial hypertension. The Phytochemical studies show that the aqueous foliar extract of Nephrolepis biserrata consists of phenolic constituents, terpeniques and nitrogenous. This extract was used to realize all the tests of our study. The contraction is recorded by a system of isolated organ. NB (5-200 mg/ml) provoke the decrease of the contraction of the aorta of the toad induced by the norepinephrine (10-6 M) in presence and in absence of the endothelium. The threshold of the effect is 5 mg/ml in the presence and 50 mg/ml in absence of endothelium; a maximal decreas.. View More»
  DOI: 10.4172/2167-0412.1000220

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