Journal of Clinical Trials
Open Access

Leila Ghahramani

Publications

• Research Article
  Comparison of the Therapeutic Effects of Rectal Diclofenac Sodium and Intramuscular Pethidine Injection in the Treatment of Acute Renal Colic: A Randomized Clinical Trail
  Author(s): Mohammad Mehdi Hosseini, AlirezaYousefi, Leila Ghahramani, Mohsen Rastegari and Abdoul-Rasoul Ebrahimi Mohammad Mehdi Hosseini, AlirezaYousefi, Leila Ghahramani, Mohsen Rastegari and Abdoul-Rasoul Ebrahimi
  
  Objectives: Renal colic is a type of abdominal pain commonly caused by obstructive stones. The aim of this study was to compare the safety and efficacy of rectal diclofenac sodium (RDS) and intramuscular pethidine (IMP) injection in acute renal colic. Materials and Methods: In an interventional prospective double-blind randomized clinical trial, 541 patients who had referred to our center because of acute renal colic were divided into two groups: (1) RDS with 266 participants and (2) IMP with 275 participants. Pain relief was measured by asking the participants at 10, 20 and 30 minutes after taking each drug. Results: In RDS group, analgesic effects of RDS were apparent in 121 participants (45.5%) after 10 min, in 191 participants (71.9%) after 20 min and in 233 participants (87.5%) after 30 min. 33 participants (12.5%) had no response to RDS. In IMP group, analges.. View More»
  DOI: 10.4172/2167-0870.1000225

  Abstract PDF

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