ISSN: 2167-0501
+44-77-2385-9429
Liang Guina
China
Research Article
A Novel Application of Wutou (Aconitum carmichaeli) and Banxia (Pinellia ternat) Aqueous Extract on Wound Healing of Rats
Author(s): Xia Xichao, Liu Hongyang, Wang Weina, Liu Fei, Hu Qingfu, Liang Guina, Zhang Dong and Liu Rongzhi
Xia Xichao, Liu Hongyang, Wang Weina, Liu Fei, Hu Qingfu, Liang Guina, Zhang Dong and Liu Rongzhi
Objective: The purpose of current study was to investigate effects of application of Wutou and Banxia aqueous extract in the wound rats.
Methods: Rats were fulfilled a surgical lesion with a 2.0 cm resecting tissue in the dorsal fascia. Following, animals were divided into 3 groups, including model group, control group treated with 1 mg/mL of Yunnan Baiyao, and Wutoubanxia group administrated 1 mg/mL of Wutou and Banxia extract. Wound contractions in day 0, 3, 7, 11 were calculated by an image analyzer. The histological analysis was detected using hematoxilin and eosin. The levels of tumor necrosis factor α (TNF-α), interleukin-2 (IL-2), transforming growth factor-β1 (TGF-β1), and basic Fibroblast Growth Factor (bFGF) transcripts in the wound tissue were determined by real-time quantitative PCR.
Results: Compared with the control gro.. View More»
DOI:
10.4172/2167-0501.1000140