Translational Medicine
Open Access

Lingling Xu

Publications

• Research Article
  Chinese FDA Approved Fungal Glycan-Based Drugs: An Overview of Structures, Mechanisms and Clinical Related Studies
  Author(s): Zijing Zhou, Zhangrun Han, Yangyang Zeng, Meng Zhang, Yidi Cui, Lingling Xu and Lijuan Zhang Zijing Zhou, Zhangrun Han, Yangyang Zeng, Meng Zhang, Yidi Cui, Lingling Xu and Lijuan Zhang
  
  Edible mushrooms have been used not only as food and nutraceuticals but also as important ingredients in traditional Chinese medicines for centuries. Pharmaceutical active components from different types of mushrooms have been extracted and studied by scientists all over the world during the past 50 years, and many biological functions, such as antitumor, immunomodulating, anti-oxidative, anti-inflammatory, and hypoglycemic activities, have been reported in peer reviewed English journals. Interestingly, the purified polysaccharides or glycans possess many reported functions of medicinal mushrooms, which make them potential drug candidates. However, glycans are a mixture of polysaccharides having variable numbers of monosaccharides, linkages, and molecular weight distributions as well as multiple biological functions that are hard to conceive as drugs by conventional standard in that a.. View More»
  DOI: 10.4172/2161-1025.1000141

  Abstract PDF

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