ISSN: 2161-1068
+44 1478 350008
Lobelia Samavati
Division of Pulmonary, Critical Care and Sleep Medicine, Wayne State University School of Medicine,
3990 John R, 3 Hudson, Detroit, MI 48201
Tanzania
Commentary
T7 Phage Display Library a Promising Strategy to Detect Tuberculosis Specific
Biomarkers
Author(s): Harvinder Talwar, Jaya Talreja and Lobelia Samavati
Harvinder Talwar, Jaya Talreja and Lobelia Samavati
One-third of the world's population is infected with tuberculosis, only 10% will develop active disease and the remaining 90% is considered to have latent TB (LTB). While active TB is contagious and can be lethal, the LTB can evolve to active TB. The diagnosis of TB can be challenging, especially in the early stages, due to the variability in presentation and nonspecific signs and symptoms. Currently, we have limited tools available to diagnose active TB, predict treatment efficacy and cure of active tuberculosis, the reactivation of latent tuberculosis infection, and the induction of protective immune responses through vaccination. Therefore, the identification of robust and accurate tuberculosis-specific biomarkers is crucial for the successful eradication of TB. In this commentary, we summarized the available methods for diagnosis and differentiation of active .. View More»
DOI:
10.4172/2161-1068.1000214