Journal of Leukemia
Open Access
ISSN: 2329-6917
+44 1300 500008
ISSN: 2329-6917
+44 1300 500008
Research Article
Long-term Outcomes in Patients with Chronic Lymphocytic Leukemia Treated with Standard Therapy
Author(s): Alvarado Ibarra Martha, Mena Zepeda Veronica, Ortiz Zepeda Maricela, Alvarez Vera José, Espitia RÃos Maria, Jiménez Alvarado Rosa and Lopez Hernández Manuel Antonio
Alvarado Ibarra Martha, Mena Zepeda Veronica, Ortiz Zepeda Maricela, Alvarez Vera José, Espitia RÃos Maria, Jiménez Alvarado Rosa and Lopez Hernández Manuel Antonio
The purpose of this study was to report the therapeutic results obtained from prospective protocols at the Hematology Service of our hospital, over the course of this century, before new drugs were used. All patients underwent chemotherapy (only one recent group also received rituximab).
All LCL patients taken care of at the Hematology Service of the National Medical Center (CMN) ?20 de Noviembre?, ISSSTE. Patients included in this study were diagnosed with LCL and met the following criteria: persistent lymphocytosis above 5 × 109/L, for more than three months; typical lymphocytic morphology, with less than 10% of immature forms; immunophenotype of B strain with CD5, CD19, CD 79a, CD 20, CD22, CD23, CD24, CD25 + low-intensity SmIg; 30%+ lymph cells in the bone marrow.
From 2001 to late 2016, 2?857patients were taken care of de novo. Out of these patients, 61 were diagnosed with LCL.. View More»
DOI:
10.4172/2329-6917.1000246