Clinical & Experimental Cardiology
Open Access

Luis Marcelo Rodrigues Paz

Publications

• Research Article
  Renal Sympathetic Denervation in Mild to Moderate Chronic Kidney Disease Patients with Chronic Heart Failure Refractory to Cardiac Resynchronization Therapy: A Safety Evaluation Study
  Author(s): Gustavo Ramalho e Silva, Luis Marcelo Rodrigues Paz, Gladyston Luiz Lima Souto, and Marcio Galindo Kiuchi* Gustavo Ramalho e Silva, Luis Marcelo Rodrigues Paz, Gladyston Luiz Lima Souto, and Marcio Galindo Kiuchi*
  
  Background: Heart failure (HF) is a challenging disease to control. Chronic overactivation of the sympathetic nervous system occurs early in HF and chronic kidney disease (CKD). The aim of this study was to evaluate the safety and effects of renal sympathetic denervation (RSD) in reducing lesions on the heart and kidneys in patients with CKD and HF refractory to cardiac resynchronization therapy (CRT). Methods and results: Twenty-one patients were included and treated with a standard irrigated cardiac ablation catheter. RSD was performed by a unique operator. All the patients included in the study had HF in functional New York Health Association (NYHA) class III, were refractory to CRT, and had mild-to-moderate CKD. Data were obtained at baseline, and at 6 and 12 months of follow-up. RSD was safe and feasible to perform in this population. No c.. View More»
  DOI: 10.4172/2155-9880.1000441

  Abstract PDF

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