ISSN: 2376-0419
+44 1300 500008
Luna Coelho HL
Brazil
Research Article
Taste acceptance of Captopril and Furosemide Extemporaneous Oral Pediatric Formulations among Hospitalized Children
Author(s): Medeiros MDSG, Garruti DDS, Batista LAA, Cruz Fonseca SGD, Fernandes FP, Luna Coelho HL
Medeiros MDSG, Garruti DDS, Batista LAA, Cruz Fonseca SGD, Fernandes FP, Luna Coelho HL
Many pediatric patients require medications that are not available in age appropriate formulations, especially those with cardiovascular diseases. The use of a suitable vehicle is critical for the preparation of extemporaneous formulations with the expected effect. Considering that palatability is essential to treatment adherence in children, we analyzed the acceptance of extemporaneous formulations of Captopril and Furosemide prepared using a developed vehicle in three flavors: neutral, strawberry and mint. Formulations were administered to hospitalized pediatric patients as prescribed. Acceptance was evaluated through the guardians using the hedonic scale and compared with the researcher’s observation. Formulations in neutral and strawberry flavors were considered acceptable for both drugs. Correlation between results from both methods was moderate for .. View More»
DOI:
10.4172/2376-0419.1000156