ISSN: 2155-6148
Madhu Mala
Bangalore Medical College, BMCRI, KR market, Bangalore, Karnataka 560002
India
Research Article
Comparison of the Effectiveness of Unimodal Opioid Analgesia with Multimodal
Analgesia in the Management of Postoperative Pain in Patients Undergoing
Surgery under Spinal Anesthesia-Double Blind Study
Author(s): Madhu Mala, Prabha Parthasarathy and Raghavendra RaoMadhu Mala, Prabha Parthasarathy and Raghavendra Rao
Objective: To evaluate the efficacy and safety of opioid analgesic alone or in combination with a Non-steroidal Anti-inflammatory Drug (NSAID) in management of post-operative pain after regression of spinal anesthesia. Methods: In this double-blind study, 120 patients who underwent infra-umbilical surgeries under spinal anesthesia were chosen for the study and were randomly allocated into 4 groups of 30 each. Each group received Tramadol 100 mg or Pentazocine 30 mg or Tramadol 100 mg+Piroxicam 20 mg or Pentazocine 30 mg+Piroxicam 20 mg intramuscularly, 30 minutes after the end of the surgery. The primary efficacy end points were the total duration of post-operative analgesia and the intensity of pain relief in different groups, as assessed by VAS. Level of sedation and incidence of side effects were observed as secondary outcomes. Results: The mean VAS scores of the patients in Pentaz.. View More»
DOI:
10.4172/2155-6148.1000673