Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
ISSN: 2155-9570
Mahdi Nili
West Indies
Research Article
Efficacy of Intravitreal Injection of Tissue Plasminogen Activator on Improvement of Visual Acuity and Decreasing the Rate of Complications in Retinal Vein Occlusion
Author(s): Ahmad Mirshahi, Mahnaz Abdollahian, Alireza Lashay, Abed Namavari, Hooshang Faghihi and Mahdi NiliAhmad Mirshahi, Mahnaz Abdollahian, Alireza Lashay, Abed Namavari, Hooshang Faghihi and Mahdi Nili
Purpose: to evaluate the effect of Intravitreal tissue plasminogen activator (r-tPA) injection on improvement of visual acuity and decreasing the rate of complications in Branch Retinal Vein Occlusion (BRVO) and ischemic Complications in Retinal Vein Occlusion (CRVO). Methods: 10 patients with BRVO and 19 patients with ischemic CRVO of recent onset (from 4 to 30 days duration) and visual acuity of <=20/50 were given 100 microgram of tPA intravitreally. Ischemia was defined as an area of nonperfusion >=10 DD for CRVO and >=5 DD for BRVO. Follow up schedule contained 6 visits : at the time of injection, and 1 week,1 month, 2months, 3months, and 6 months after. Fluorescein angiography was performed before injection and at the end of the study. Results: In ischemic CRVO group: only one eye (5.6%) developed Iris neovas.. View More»
DOI:
10.4172/2155-9570.1000228