Journal of Clinical Trials
Open Access

Mahmoud A Sabour

Publications

• Research Article
  Assessment of Human Natriuretic Peptides (B), Human N-Terminal Pro-BNP and Nor-epinephrine as Neurohumoral Markers in Sleep Disordered Breathing among Heart Failure Patients in Upper Egypt
  Author(s): Suzan Salama, Amany Omar, Mohamed Ismail Seddik, Mahmoud A Sabour and Doaa Magdy Suzan Salama, Amany Omar, Mohamed Ismail Seddik, Mahmoud A Sabour and Doaa Magdy
  
  Objective: The purposes of this study are to: (1) Measure neurohumoral activation in heart failure patients with and without Sleep Disordered Breathing; (2) Assessment of neurohumoral markers with the severity of sleep apnea and severity of heart failure. Patients and methods: In this case report study, we studied 100 patients with heart failure (64 male, 36 female). All patients underwent echocardiography and a full night-attended polysomnography, in addition to neurohumoral evaluation. Results: Group (1) sleep Disordered Breathing (SDB) had significant increase in the plasma concentration level of BNP (591.50 ± 165.75 vs. 298.33 ± 86.63 pg/ml, P=0.001*), NT-proBNP (1750.05 ± 773.15 vs. 686.98 ± 377.88 pg/ml, P=0.001*) and nor epinephrine (NE) (616.12 ± 139.57 vs. 203.80 ± 64.30.. View More»
  DOI: 10.4172/2167-0870.1000333

  Abstract PDF

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