Journal of Clinical Toxicology
Open Access

Mamiko Koshiba

Publications

• Research Article
  Multivariate PCA Analysis Combined with Ward’s Clustering for Verification of Psychological Characterization in Visually and Acoustically Social Contexts
  Author(s): Koki Mimura, Yuka Shirakawa, Shun Nakamura and Mamiko KoshibaKoki Mimura, Yuka Shirakawa, Shun Nakamura and Mamiko Koshiba
  
  The development of the nervous system is a process of gene-environment interaction through prenatal and neonatal stages. The chemical environment may cause mal-development of the social brain network leading to developmental disorders. Thus, we need to develop a new behavioral method which distinguishes the subtle difference in early stage development of sensory-motor, socio-emotional, and cognitive processing in humans and animal models. Here, we have developed an innovative tool for signal processing to structuralize the behavioral elements from a large body of complex information via the multivariate analysis (principal components analysis combined with Ward’s clustering) using an animal model (domestic chicks) and found dynamical differences of combined behavioral parameters over social contexts between socially affiliated chicks and isolated chicks. We prepared two groups e.. View More»
  DOI: 10.4172/2161-0495.1000157

  Abstract PDF

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