ISSN: 2155-9880
+44 1300 500008
Manal A Mohamed
Egypt
Research Article
The Clinical Value of Copeptin in Acute Coronary Syndrome
Author(s): Nora M Aborehab, Tarek M Salman, Ola S Mohamed, Abdel Rahman H El Boquiry and Manal A MohamedNora M Aborehab, Tarek M Salman, Ola S Mohamed, Abdel Rahman H El Boquiry and Manal A Mohamed
(1) The introduction of a novel immunoassay measuring copeptin, the c-terminal part of the vasopressin prohormone provided a unique window in common medical disorder. We examined the ability of copeptin in combination with cardiac troponin-I (cTn-I) in diagnosis of AMI, the differentiation between AMI and UA and finally evaluate the ability of copeptin in enhancing sensitivity of cTn-I at early hours of admission in emergency department.
(2) This study was carried on 50 subjects; they were divided into 33 patients with AMI and 17 patients with UA. Concentrations of copeptin, cTn-I and CK-MB were determined in their sera.
(3) In AMI group, the mean serum level of copeptin was highly significant in three hours than admission time and six hours. The mean serum level of cTn-I was highly significant in six hours than the admission time and three hours. The sensitivity and s.. View More»
DOI:
10.4172/2155-9880.1000278