Journal of Clinical and Cellular Immunology
Open Access

Manal Mohamed Saber

Publications

• Research Article
  Evaluation of the Diagnostic Performance of Soluble Human Leukocyte Antigen- G versus α-Fetoprotein for Hepatitis C Virus-Induced Hepatocellular Carcinoma
  Author(s): Amel Mahmoud Kamal Eldin, Manal Mohamed Saber, Aliaa Higazi, Amal Kamal Helmy, Hala Ibrahem Mohamed and Asmaa Ahmed Aly Amel Mahmoud Kamal Eldin, Manal Mohamed Saber, Aliaa Higazi, Amal Kamal Helmy, Hala Ibrahem Mohamed and Asmaa Ahmed Aly
  
  Background: Hepatocellular carcinoma (HCC) is the leading cause of death in HCV-related liver diseases and the third most common cause of cancer-related mortality worldwide. A reliable serum marker for early diagnosis of HCC is currently lacking. Objectives: The aim of this study was to identify the serum levels of soluble Human leukocyte antigen-G (sHLAG) in HCC and liver cirrhosis (LC) patients. As well, we aimed to estimate the diagnostic performance of sHLA-G for HCC by comparing its levels with the levels of Alpha fetoprotein (AFP). Subjects and methods: The study included 100 subjects divided into: 25 apparently healthy volunteers who served as healthy control subjects (group I), and 50 patients with untreated HCC on top of liver cirrhosis (group II) in addition to 25 cirrhotic patients (group III). HCC group was d.. View More»
  DOI: 10.4172/2155-9899.1000433

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