Department of Radiation Oncology and Comprehensive Cancer Center, the Ohio State University, Columbus, OH43210, USA
Biography
Manchao Zhang has started working on cancer immunotherapy in the 1990s, received rigorous immunological training from Dr. John E. Coligan at NIAID/NIH, dissected the molecular mechanism of action of the TNF super-family member, Light, for the first time reported that a small molecule natural compound as an orally available Bcl-2 family member inhibitor anticancer drug, identified so far the most potent Grb2 SH2 domain antagonist small molecule inhibitors, validated two dozens of anticancer drug targets.
